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KMID : 1007520150240020689
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Food Science and Biotechnology
2015 Volume.24 No. 2 p.689 ~ p.697
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DNA Protection and Antioxidant and Anti-inflammatory Activities of Water Extract and Fermented Hydrolysate of Abalone (Haliotis discus hannai Ino)
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Md. Abul Hasnat
Mehnaz Pervin
Kim Da-Hye
Kim Young-Jun
Lee Jeong-Jun
Pyo Han-Jong
Lee Chung-Woo
Lim Beong-Ou
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Abstract
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Antioxidant and anti-inflammatory activities of water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino) were examined. Experimental models were used to characterize the antioxidant activities, which were compared with the standard antioxidants α- tocoferol and EDTA (ethylenediamine tetraacetic acid). Antioxidant activities of water extract and fermented hydrolysate were examined at the cellular level and evaluated for anti-inflammatory activities in LPS (lipopolysaccharides)- stimulated murine RAW 264.7 macrophages. Production of the pro-inflammatory mediators nitric oxide (NO) and prostaglandin (PGE2) was significantly (p<0.05) inhibited by treatments with abalone water extract and fermented hydrolysate, compared with controls. Abalone (Haliotis discus hannai Ino) can be considered as a potential source of natural antioxidants and dietary supplements.
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KEYWORD
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abalone, antioxidant, anti-inflammatory, fermentation, DNA
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